As this was a pragmatic trial, the content of therapy sessions provided to participants receiving usual care (provided over 5 or 7 days a week) was not mandated.
Broad guidelines were provided for the organisation and content of circuit class therapy sessions via an intervention manual. For example, the manual states that activities should be goal directed, tailored to the individual participant, and progressed; and that the time spent in active task practice should be maximised during therapy sessions. In order to assess adherence to the trial protocol and intervention fidelity, selected therapy sessions, both individual and circuit class therapy sessions were videoed in their entirety. Data collected during these sessions were used to describe the content of physiotherapy provided in detail. The specific questions to be answered with these data were: (1) What is the content of individual therapy sessions and group circuit class sessions provided HKI-272 clinical trial to people receiving physiotherapy rehabilitation after stroke, in terms of total active and rest time, time
spent practising specific tasks, and number of steps taken? This observational study was embedded within a randomised trial. Full details of the CIRCIT trial protocol have been published.7 Recruitment for PARP inhibitor review the CIRCIT trial commenced in July 2010 and finished in June 2013. Data collection for the current observational study occurred during four time periods throughout the trial (September/October 2010, December 2010 to February 2011, August/September 2012, and December 2012 to January 2013). The time periods and specific days on which therapy sessions were videotaped were based on research assistant staff availability. The CIRCIT trial participants were people with a stroke of moderate severity who were admitted to an inpatient rehabilitation facility, and who were able to walk independently (with or without a walking aid) prior to their stroke.7
Moderate stroke severity was defined as either a total Functional Independence Measure (FIM) score of between 40 and 80 points, or a motor sub-score of the FIM of 38 to 62 points at the time of recruitment to the trial. Physiotherapy sessions were videoed in their entirety. Standard definitions were used to identify the beginning and end of therapy sessions, as presented in Box 1. The videos were viewed of and data regarding content of therapy extracted. Definitions of physical activity and inactivity were also standardised, as presented in Box 1, and categorised, as presented in Box 2. This method of video analysis has been shown to have acceptable intrarater reliability.6 Total active time was determined as the sum of time spent in each category of physical activity. Total inactive time was determined as total therapy time minus total active time. The number of steps participants took during the physiotherapy sessions was also analysed in a subsample of the videos.